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THM Show 009 – Dan Pardi, Sleep Deprivation, Reaction Time, Impulsivity, Memory Formation, Hormone Regulation

 

Summary:

Welcome to The Hacked Mind show! This week I interview Dan Pardi of Dan’s Plan. Dan does research at Stanford University and Leiden University in the Netherlands. His research focuses on on cognitive neuroscience and neurobiology. He has been invited to speak at numerous international health conferences (including Paleo FX and Ancestral Health Symposium).

This episode we will cover:

1. Reaction time, impulsivity, and mood after sleep deprivation
2. Memory storage with sleep deprivation
3. Hormone regulation of leptin and ghrelin
4. Sleep loss and impaired glucose regulation
5. Modern environment and ancestral wellness

By the way, you can enter your best email address in the panel on the side or below and get a FREE ebook Brain Hacking 101: 12 Tangible Ways to Correct Your Neurotransmitter and Hormonal Balance Now.

Discussion Topics

[2:32] Hormones in narcolepsy patients – missing brain protein
[4:35] Reaction time, mood, impulsivity – how sleep relates to eating behavior
[5:45] Dan’s new study – Slower reaction time after sleep deprivation
[7:11] Effort discounting – less likely to work for something you would otherwise work for
[9:55] How healthfully did subjects eat? Based on the users’ belief of health (health score)
[14:07] General reaction time problems from research; not linear decline in reaction time. Possible to focus, but not sustained periods
[16:59] Information entering the brain as a diffusion process; info moves slower throughout the brain and it is harder to learn new info
[17:45] Brian Wansink – “Mindless Eating”, over 200 food decisions made per day
[19:58] How memories are formed – storage in neural networks, pruning memories no longer needed (forgetting is good!)
[22:00] Encoding, consolidation, retrieval – sleep impacts all aspects of memory
[23:28] People who are obese have poor recall of foods eaten in the day; is obesity a memory problem?
[28:44] Impaired glucose regulation; sleep loss leads to glucose of pre-diabetic
[29:25] Leptin + ghrelin – regulating fat loss/brain signalling
[32:29] Aspects of modern food environment that shut down signals and make us consume more than usual
[33:09] Better at fat gain than fat loss
[33:32] Altered 24 hour profile for leptin and ghrelin; sleep deprivation = lower leptin, higher ghrelin, which both signal to burn less and consume more
[37:42] Modern lifestyle discordance with what the body genetically wants
[39:06]Dan’s Plan – tools for healthier living/tracking

External Mentions

Dan’s Plan
Mindless Eating book
David Dinges, PhD

Thank You

Thank you for listening and supporting The Hacked Mind show! Please consider leaving a review on iTunes if you liked what you heard. Also, you can get my free ebook just by entering your email address on the right of your screen or below this post. Once again, thanks for listening and see you next week!

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